What Is the Ideal Cholesterol Level?
Results of ongoing current research are driving the recommended level lower and lower.
By Joel Fuhrman, M.D.
The ideal cholesterol level
would be one that prevents
the formation of cholesterol
deposits and actually promotes the
reversal of the cholesterol plaques
that could be present.
In recent years, Americans have
received constantly changing advice
about what constitutes a “normal”
cholesterol level. The American
Heart Association has changed their
recommendations multiple times
during the last ten years, gradually
lowering the level they consider to
be a risk indicator for heart disease.
In the past, drug therapy was recommended
only for those with an
LDL cholesterol above 160. Today,
the level is much lower.
Most recently, the National Cholesterol
Education Program has
updated their Adult Treatment Panel
(ATP) III guidelines, based on evidence
derived from recent statin trials
and published them in the July 12,
2004 issue of Circulation. The updated
recommendations, which are
endorsed by The National Heart,
Lung, and Blood Institute, the
American College of Cardiology, and
the American Heart Association, suggest
that more intensive cholesterol
treatment is an option for people at
high risk for myocardial infarction
(MI) and cardiovascular death.
“The lower the better for high-risk
people,” Scott Grundy, M.D., Ph.D.,
representative for the American
Heart Association, said in a news release.
“That’s the message on lowdensity
lipoprotein (LDL) cholesterol
from recent clinical trials.”
The last set of guidelines in 2001
encouraged physicians to treat highrisk
individuals with an LDL cholesterol
greater than 130 with a goal to
bring their LDL cholesterol below
100.The newest guidelines encourage
treatment with medication for
all heart patients whose LDL is
above 100, with a goal to bring
their LDL below 70.
Average Total
Cholesterol Levels in
Animals and Humans
Baboon. . . . . . . . . . . . . 110
Howler monkey . . . . . ... 100
Elephant. . . . . . . . . . . . 110
Rhinoceros. . . . . . . . . . . 80
Pygmy tribes . . . . . . . .. 100
Hazda tribes . . . . . . . . ..110
Rural Chinese . . . . . . . . 125
Adult Americans . . . . . .. 208
These latest recommendations
occurred as a result of drug trials
that illustrated fewer cardiac events
and fewer deaths in heart patients
whose cholesterols were driven to
those very low levels with drugs.
The reason they only recommend
these aggressive numbers for highrisk
patients, and not all people, is
that achieving these low levels has
to be balanced against the cost and
side effects of treatment that often
requires high doses of medication
or combination therapy with a variety
of medications.
The rest of the story
So are these authorities correct? Is
an LDL cholesterol below 70 ideal,
or are they taking this cholestero lowering
advice too far, just to push
medication and doctoring?
First of all, keep in mind that a
person’s cholesterol level is not the
only factor that permits the development
of atherosclerosis. Atherosclerosis
is a complex process
involving a myriad of risk factors,
including low antioxidant intake,
excess caloric consumption, and
lack of adequate exercise. In order
to maximally preclude the possibility
of heart disease, we have to do
more than merely lower cholesterol
with drugs. The toxic standard
American diet (which has
spread to other countries) has
enabled heart disease to emerge as
the number one killer of the
human species, yet this problem is
never seen in wild animals. Evidence
from early human civilizations
also has shown no evidence
of heart disease or atherosclerosis,
even in people in their seventh and
eighth decades of life.
Wild animals, as well as early
humans, all demonstrate total cholesterol
levels between 90 and 150,
and LDL cholesterol between 50
and 75. High cholesterol is strictly a
modern phenomenon, the result of
our toxic food environment.
The mean cholesterol level of
modern Westernized humans is
about twice the values seen in
infants, wild animals, and primitive
populations eating wild, natural
food. (See chart.) Healthy infants
run LDL cholesterol levels in the 30
to 70 range, about the same as
healthy primates in the wild and
other wild animals.
Recent interventional trials on
cholesterol lowering in modern
countries found that the further we
push the LDL cholesterol down, the
larger the degree of regression of coronary artery disease observed.
In other words, dropping the
LDL cholesterol to 80 showed dramatic
reversal of disease that was
not seen when LDL cholesterol
was lowered to 110. In fact, moderate
LDL lowering to 110 allowed
for continued progression of disease
for most people.
If we combine the data from
all of these modern trials,we find
that the level of LDL reduction at
which the cardiac event rate can
be predicted to approach zero is
in the 50 to 70 range, the same
range we see in wild animals and
early humans.
Furthermore, the effect of dramatic
LDL reduction was so profound
at preventing heart attacks
at this lower range that we can
theorize that LDL cholesterol is a
required catalyst in the atherosclerosis
process, whereby extremely
low LDL may prevent coronary
heart events regardless of other
risk factors. Reversal and protection
may be available for the
majority with a cholesterol of 110
or lower if they were eating a truly
heart-healthy diet; however, without
a great diet, more cholesterol
lowering clearly is needed.
My observations of those following
my nutritional guidelines
for a vegetable-based, high-nutrient
density diet over a long term
(10 years or more) has illustrated
that people routinely achieve the
numbers seen only in childhood
and in wild animals.
The bottom line is that the vast
majority of our population develops
hardening of the arteries, and
the entire so-called “normal” range
pathologic.Truly healthy LDL cholesterols
are certainly below 80.
The modern target of 100 mg/dl
for LDL is a great goal considering
how far above that our population
is at present, but if you have heart
disease and truly want to maximally
reverse your condition and protect
your life, a better goal would
be an LDL cholesterol below 70.
This is not driving cholesterol
too low; it merely is bringing it
down to the levels seen in all
healthy animals (and humans)
with no signs of atherosclerosis.
Of course,you must keep in mind
it is impossible to drive the cholesterol
that low with conventional
dieting. The studies referenced
above relied on cholesterol
lowering drugs.
The only way to achieve lipid
levels that low without drugs is to
use the vegetable-based dietary approach
described in my books,Eat
To Live and Cholesterol Protection
For Life. No other dietary approach
has been demonstrated to
drop cholesterol levels as powerfully
as drugs. By using nutritional
excellence with the judicious use
of natural cholesterol-lowering
supplements,we can reap full benefits
and remove the risk of heart
disease, without the dangers of
cholesterol-lowering medications.
Nutritional excellence
versus medication
A crucial piece of evidence to
consider is that most studies documenting
the benefits of cholesterol-
lowering drugs for heart
patients do not document a statistically
significant increase in
life span for those who did not
have heart disease. For example,
in the PROSPER study, the 22
fewer deaths for vascular disease
in the pravastatin group were offset
by an increase of 24 deaths
from cancer.5 Unlike the drug
approach, when you lower your
cholesterol naturally, you get a
dramatic reduction in both heart
attack and cancer mortality. This is why my nutritional recommendations
for cholesterol lowering
are the only choice for intelligent
individuals. All people should be
aware that we can eliminate cardiac
risk and dramatically lower
cholesterol without needing to
resort to medications with risky
side effects. Unfortunately, this
information is still hidden from
the public.
When you first maximize your
cholesterol levels with high green
vegetable intake and other nutrient
rich foods, you remedy other
factors that promote disease causation
and receive an even more
dramatic reduction of heart problems
and other diseases normally
associated with aging in modern
societies. Not only will you avoid
heart disease, you also will prevent
stroke, diabetes, dementia,
macular degeneration, arthritis,
osteoporosis, cancer, and other
typical degenerative diseases.